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刘国东教授简介


  发布时间: 2015-03-17   信息员:   

  

刘国东,男,1972年出生,博士,现任美国北达科他州立大学(North Dakota State University)化学与生物化学系副教授,福建农林大学闽江学者讲座教授。在Journal of the American Chemistry SocietyAnalytical Chemistry Biosensors and BioelectronicsChemical Communications等分析化学领域顶级期刊上发表了SCI论文70余篇,这些论文被SCI期刊他人正面引用1000余次。现为Nano-Bio-Analysis杂志编委,美国化学学会、科学发展协会和电分析化学协会会员并应邀担任“Frontier in Bioscience”, “Analytical Chemistry”, “Journal of American Chemistry Society”“Electrochemistry Communication” “Chemical Communications”“Electroanalysis”“Analytical Chimica Acta”“Journal of Nanoscience and Nanotechnology”“Analyst” 等杂志审稿人。获得20062007年度太平洋西北国家实验室杰出工作奖章,以及2010-2012北达科他州立大学杰出研究奖等。

受教育经历:

2004/10-2006/09 美国Pacific North West National Laboratory 生物分析化学 博士后

2002/01-2004/09 美国New Mexico State University 生物分析化学 博士后

2001/06 湖南大学 生物分析化学 博士学位

1998/07 湖南大学 分析化学 硕士学位

1995/07 湖南师范大学 分析化学 学士学位

研究工作经历:

2013-至今 美国North Dakota State University 副教授

2007-2013 美国North Dakota State University 助理教授

2006-2007 美国Pacific Northwest National Laboratory 研究员

研究方向和领域:

研究领域主要为构建基于纳米材料的生物传感器、生物分析方法和现场检测装置,应用于生物医药中核酸、蛋白质超灵敏检测,食品安全检测,临床即时检测以及环境监测等。

硕士生导师招生学科介绍:

1. 食品科学

2. 农业推广(食品加工与安全领域)

科研项目:

1. “Development of Hand-Held Cancer Biomarker Monitor” (NIH, R21, 5R21CA137703-02) 项目负责人2010/09/01-2014/04/30.

2. “Development of Lateral Flow Nucleic Acid Biosensors for the Detection of HPV” (DakotaBio Corp, Industry Research Funds, FAR0020201),项目负责人,2012/08/01-2015/02/28.

3. “Conjugates of Quantum Dots and Natural Iron Complexes for Detecting Gram-negative Pathogens and Probing Membrane Transport Mechanisms” (Center of Protease Research NDSU, COBRE Pilot Project, FAR0020201), 项目负责人,2013/03/01-2014/06/30.

4. “Arrayed Lateral Flow Biosensor for Rapid Molecular Identification of UTI-Related” (Lynntech Inc, SBIR subcontract, 1 R43 AI102357-01), 项目负责人, 2012/09/01-2013/05/31.

5. “A POC Field Test for the Rapid Determination of Folate Insufficiency (SBIR, Phase I)” (Lynntech Inc, SBIR subcontract, 200-2012-M-52272), 项目负责人, 2012/09/01-2013/05/31.

6. “Rapid and Cost-Effective Diagnostic System for Sexually Transmitted Infections” (Lynntech Inc, NIH SBIR subcontract), 项目负责人, 2011/12/01-2012/05/31.

7. “An Integrated Optical DNA Detector for Portable PCR” (Lynntech Inc, NIH SBIR subcontract), 项目负责人, 2010/01/01-2010/05/31.

8. “Innovative Biomonitoring Device for Rapid Diagnosis of Exposure to Nerve Agents” (Pacific Northwest National Laboratory, NIH U01 subcontract), 项目负责人, 2007/01/11-2010/05/30.

9. “North Dakota State University New Faculty Start up” (North Dakota State University, Start-up funds), 项目负责人, 2007/08/01-2009/07/31.

10. “Development of Point-of-Care Nucleic acid Biosensors for Clinical Diagnosis” (NIH INBRE Lynntech Inc, Seed grant), 项目负责人, 2008/09/01-2009/04/30.

11. “Integrated Nucleic acid and Protein Biosensors for Cancer Early Diagnosis” (Center of Proteases Research NDSU, CPR Seed grant), 项目负责人, 2009/01/01-2009/05/30.

12. “Portable Analyzer for on-site Monitoring of worker Exposure to Toxic Metal” (Pacific Northwest National Laboratory, NIH R21 Sub-contract), 项目负责人, 2008/01-2008/07.

近年发表的学术论文:

1. Qiu, W.; Xu, H.; Takalkar, S.; Gurung, A. S.; Liu, B.; Zheng, Y.; Guo, Z.; Baloda, M.; Baryeh, K.; Liu, G.* “Carbon nanotube-based lateral flow biosensor for sensitive and rapid detection of DNA sequence.” Biosensors and Bioelectronics 2015, 64, 367-372.

2. Xu, H.; Chen, J.; Birrenkott, J.; Zhao, J. X.; Takalkar, S.; Baryeh, K.; Liu, G.* “Gold-nanoparticle-decorated silica nanorods for sensitive visual detection of proteins. “ Analytical Chemistry 2014, 86, 7351-7359.

3. Gao, X.; Xu, H.; Baloda,M.; Gurung,A. S.; Xu, L.; Wang, T.;Zhang, X.;Liu, G.* “Visual Detection of microRNA with Lateral Flow Nucleic Acid Biosensor.” Biosensor and Bioelectronics 2014, 54, 578-584.

4. Shen, G.; Xu, H.; Gurung, A. S.; Yang, Y.; Liu, G. * “Lateral Flow Immunoassay with the Signal Enhanced by Gold Nanoparticle Aggregates Based on Polyamidoamine Dendrimer.” Analytical Sciences, 2013, 29, 799-804.

5. Xu, L.; Wang, S.; Dong, H.; Liu, G.; Wen, Y.; Wang S.; Zhang, X. “Fractal gold modified electrode for ultrasensitive thrombin detection.” Nanoscale 2012 4, 3786- 3790.

6. He, Y.; Zhang, X.; Zhang, S.; Kris, K. L.; Man, F. C.; Kawde, A.; Liu, G.* “Visual detection of single-base mismatches in DNA using hairpin oligonucleotide with double- target DNA binding sequences and gold nanoparticles.” Biosensor and Bioelectronics 2012, 34, 37-43.

7. He, Y.; Zeng, K.; Zhang S.; Gurung, A. S.; Baloda, M.; Zhang, X.; Liu, G.* “Visual detection of genemutations based on isothermal strand-displacement polymerase reaction and lateral flow strip.”Biosensor and Bioelectronics 2012, 31(1), 310-315.

8. He, Y.; Zhang, X.; Zeng, K.; Zhang, X.; Baloda, M.; Gurung, A. S.; Liu G.* “Visual detection of Hg²⁺ in queou solution using gold nanoparticles and thymine-rich hairpin DNA probes.” Biosensor and Bioelectronics 2011, 26(11), 4464-4470.

9. He, Y.; Zhang, S.; Zhang, X.; Baloda, M.; Gurung, A. S.; Xu, H.; Zhang, X.; Liu, G.* “Ultrasensitive nucleic acid biosensor based on enzyme-gold nanoparticle dual label and lateral flow strip biosensor.” Biosensors and Bioelectronics 2011, 26(5), 2018-2024.

10. Fang, Z.; Huang, J.;Lie, P.; Xiao, Z.; Ouyang, C.; Wu, Q.; Wu, Y.; Liu, G.*; Zeng, L. “Lateral flow nucleic acid biosensor for Cu2+ detection in aqueous solution with high sensitivity and selectivity.” Chemical Communications 2010, 46(47), 9043-9045.

11. He, Y.; Zeng, K.; Gurung, A.; Baloda, M.; Xu, H.; Zhang, X.; Liu, G.* “Visual detection of single-nucleotide polymorphism with hairpin oligonucleotide-functionalized gold nanoparticles.” Analytical Chemistry 2010, 82(17), 7169-7177.

12. He, Y.; Zeng, K.; Zhang, X.; Gurung, A.; Baloda, M.; Xu, H.; Liu, G.* “Ultrasensitive electrochemical detection of nucleic acid based on the isothermal strand-displacement polymerase reaction and enzyme dual amplification.” Electrochemistry Communications, 2010, 12, 985-988.

13. Zhao, L.; He, Y.; Mao, X.; Sun, Y.; Zhang, X.; Li, C.; Liu, G.* “Electrochemical assay of active prostate-specific antigen (PSA) using ferrocene-functionalized peptide probes.” Electrochemistry Communications 2010, 12(3), 471-474.

 

 

 

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